NEUROGENETICSSilvia Paracchini Research Group
We are studying the genetic basis of complex cognitive and behavioural phenotypes. In particular we focus on the biology of dyslexia, a specific impairment in learning to read which is caused in large part by genetic factors. We are also interested in cognitive traits related to dyslexia such as general reading and language abilities.
More recently we have become interested in handedness and in a complex link between dyslexia and laterality. We are using large scale screening involving genome-wide and functional genomics approaches to identify candidate genes or loci underlying these phenotypes. In parallel we are developing functional assays to understand the biological mechanisms that mediate genetic differences to phenotypic variation.
We are very happy to share the results of a project conducted in collaboration with the University of Bologna, published in The FASEB Journal. With this work we identified a rare mutation in the SPART gene and leading to a form of developmental delay. Functional...
This year Away Day has been a great success. We started in St Monans Parish Church which we were lucky to find open. Just we minutes from there, we enjoyed a fantastic outdoor lunch at the East Pier Smokehouse overlooking the sea. This gave the calories to set off for...
The neurogenetics group took part to this year SoapBoxScience event in Edinburgh. SoapBoxScience is aimed at promoting the visibility of women in STEM while discussing science with the general public. Silvia was one of the speakers on a soap box. Judith and Filippo...
Silvia gave a talk at the 6th International conference on Biophotonics ICOB2019. This was a great opportunity to showcase our work on functional characterization of genes implicated in neurodevelopmental disorders.
See our latest preprint; another collaboration with Dr Marietta Papadatou-Pastou looking at the link between handedness and mathematical abilities. This is the first output by Filippo!