NEUROGENETICSSilvia Paracchini Research Group
We are studying the genetic basis of complex cognitive and behavioural phenotypes. In particular we focus on the biology of dyslexia, a specific impairment in learning to read which is caused in large part by genetic factors. We are also interested in cognitive traits related to dyslexia such as general reading and language abilities.
More recently we have become interested in handedness and in a complex link between dyslexia and laterality. We are using large scale screening involving genome-wide and functional genomics approaches to identify candidate genes or loci underlying these phenotypes. In parallel we are developing functional assays to understand the biological mechanisms that mediate genetic differences to phenotypic variation.
New paper led by Judith reporting the first GWAS for hearing abilities in children is now out in Neuropsychiatric Genetics!!! Find out more at this link .
The largest genetic study conducted to day in over a million of study participants is out as preprint on MedRxiv. The analysis was led by Dr Michelle Luciano at the University of Edinburgh and involved many research groups from the GenLang Consortium, including our...
In occasion of International Left Handers Day our work was covered in this article published in Oggi Scienza
Silvia attended the SSSR2021 (Society for Scientific Study of Reading) conference where she gave a talk and took part to a live Q&A session in a symposium on dyslexia and co-morbid disorders. More details of the conference can be found here.
We are delighted for the award of a St Andrews/Bonn collaborative grant. Through this collaboration we will extend our work looking aimed at dissecting the genetics of neurodevelopmental disorders through new computational methods. Read here about the project.